GLUTAMATERGIC DYSFUNCTION IN SCHIZOPHRENIA

Glutamatergic dysfunction in Schizophrenia

Abstract The NMDA-R Default hypofunction model of schizophrenia started with the clinical observation of the precipitation of psychotic symptoms in patients with schizophrenia exposed to PCP or ketamine.Healthy volunteers exposed to acute low doses of ketamine experienced mild psychosis but also negative and cognitive type symptoms reminiscent of t

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No increased risk of cancer associated with metal-on-metal or ceramic-on-ceramic procedures compared to other bearing surfaces in patients with total hip arthroplasty: A nationwide linked registry cohort analysis of 167,837 patients.

ObjectivesStudies have identified increased cancer risk among patients undergoing total hip arthroplasty (THA) compared to the general population.However, evidence of all-cause and site-specific cancer risk associated with different bearing surfaces has varied, with previous studies having short latency periods with respect to use of modern Metal-o

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Reconsidering the use of rankings in the valuation of health states: a model for estimating cardinal values from ordinal data

Abstract Background In survey studies on health-state valuations, ordinal ranking exercises often are used as precursors to other elicitation methods such as the time trade-off (TTO) or standard gamble, but the ranking data have not been used in deriving cardinal valuations.This study reconsiders the role of ordinal ranks in valuing health and intr

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Temperature Effects on the HOPG Intercalation Process

Tool Graphite intercalation via chemical strategies is a common procedure to delaminate stratified crystals and obtain a suspension of graphene flakes.The intercalation mechanism at the molecular level is still under investigation in view of enhancing graphene production and reducing damage to the original pristine crystal.The latter, in particular

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